Cargando…
Melatonin-Induced Protective Effects on Cardiomyocytes Against Reperfusion Injury Partly Through Modulation of IP3R and SERCA2a Via Activation of ERK1
BACKGROUND: Melatonin is a neuroendocrine hormone synthesized primarily by the pineal gland that is indicated to effectively prevent myocardial reperfusion injury. It is unclear whether melatonin protects cardiac function from reperfusion injury by modulating intracellular calcium homeostasis. OBJEC...
Autores principales: | Hu, Shunying, Zhu, Pingjun, Zhou, Hao, Zhang, Ying, Chen, Yundai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Cardiologia - SBC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831301/ https://www.ncbi.nlm.nih.gov/pubmed/29538523 http://dx.doi.org/10.5935/abc.20180008 |
Ejemplares similares
-
Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission‐VDAC1‐HK2‐mPTP‐mitophagy axis
por: Zhou, Hao, et al.
Publicado: (2017) -
The YAP/SERCA2a signaling pathway protects cardiomyocytes against reperfusion-induced apoptosis
por: Zhong, Jiankai, et al.
Publicado: (2020) -
ERK/PP1a/PLB/SERCA2a and JNK Pathways Are Involved in Luteolin-Mediated Protection of Rat Hearts and Cardiomyocytes following Ischemia/Reperfusion
por: Wu, Xin, et al.
Publicado: (2013) -
SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury
por: Tan, Ying, et al.
Publicado: (2020) -
Melatonin Attenuates Cardiac Ischemia-Reperfusion Injury through Modulation of IP3R-Mediated Mitochondria-ER Contact
por: Li, Wenya, et al.
Publicado: (2021)