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Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst

Bacillus anthracis is the causative agent of anthrax in humans and other mammals(1, 2). In lethal systemic anthrax, proliferating bacilli secrete large quantities of the toxins lethal factor (LF) and edema factor (EF), leading to widespread vascular leakage and shock. While host targets of LF (MAPKK...

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Detalles Bibliográficos
Autores principales: Guichard, Annabel, McGillivray, Shauna M., Moreno, Beatriz-Cruz, van Sorge, Nina M., Nizet, Victor, Bier, Ethan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831355/
https://www.ncbi.nlm.nih.gov/pubmed/20944747
http://dx.doi.org/10.1038/nature09446