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Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst
Bacillus anthracis is the causative agent of anthrax in humans and other mammals(1, 2). In lethal systemic anthrax, proliferating bacilli secrete large quantities of the toxins lethal factor (LF) and edema factor (EF), leading to widespread vascular leakage and shock. While host targets of LF (MAPKK...
Autores principales: | Guichard, Annabel, McGillivray, Shauna M., Moreno, Beatriz-Cruz, van Sorge, Nina M., Nizet, Victor, Bier, Ethan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831355/ https://www.ncbi.nlm.nih.gov/pubmed/20944747 http://dx.doi.org/10.1038/nature09446 |
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