Polydatin Protects Diabetic Heart against Ischemia-Reperfusion Injury via Notch1/Hes1-Mediated Activation of Pten/Akt Signaling

Diabetes exacerbates oxidative/nitrative stress during myocardial ischemia-reperfusion (MI/R) injury. Recent studies highlighted the cardioprotective actions of polydatin. However, its effect on diabetic MI/R injury and the underlying mechanisms remain unknown. This work was undertaken to evaluate t...

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Detalles Bibliográficos
Autores principales: Yu, Liming, Li, Zhi, Dong, Xue, Xue, Xiaodong, Liu, Yu, Xu, Shu, Zhang, Jian, Han, Jinsong, Yang, Yang, Wang, Huishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831600/
https://www.ncbi.nlm.nih.gov/pubmed/29636838
http://dx.doi.org/10.1155/2018/2750695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831600/
https://www.ncbi.nlm.nih.gov/pubmed/29636838
http://dx.doi.org/10.1155/2018/2750695

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