Cargando…

Polydatin Protects Diabetic Heart against Ischemia-Reperfusion Injury via Notch1/Hes1-Mediated Activation of Pten/Akt Signaling

Diabetes exacerbates oxidative/nitrative stress during myocardial ischemia-reperfusion (MI/R) injury. Recent studies highlighted the cardioprotective actions of polydatin. However, its effect on diabetic MI/R injury and the underlying mechanisms remain unknown. This work was undertaken to evaluate t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Liming, Li, Zhi, Dong, Xue, Xue, Xiaodong, Liu, Yu, Xu, Shu, Zhang, Jian, Han, Jinsong, Yang, Yang, Wang, Huishan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831600/ https://www.ncbi.nlm.nih.gov/pubmed/29636838 http://dx.doi.org/10.1155/2018/2750695

Ejemplares similares

Diallyl trisulfide exerts cardioprotection against myocardial ischemia-reperfusion injury in diabetic state, role of AMPK-mediated AKT/GSK-3β/HIF-1α activation
por: Yu, Liming, et al.
Publicado: (2017)

The Jagged-2/Notch-1/Hes-1 Pathway Is Involved in Intestinal Epithelium Regeneration after Intestinal Ischemia-Reperfusion Injury
por: Chen, Guoqing, et al.
Publicado: (2013)

MicroRNA-30e protects the heart against ischemia and reperfusion injury through autophagy and the Notch1/Hes1/Akt signaling pathway
por: Zheng, Jianjie, et al.
Publicado: (2018)

Nutritional Preconditioning of Apigenin Alleviates Myocardial Ischemia/Reperfusion Injury via the Mitochondrial Pathway Mediated by Notch1/Hes1
por: Huang, Huang, et al.
Publicado: (2019)

Post-treatment curcumin reduced ischemia–reperfusion-induced pulmonary injury via the Notch2/Hes-1 pathway
por: bo, HaiZou, et al.
Publicado: (2019)

Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway
por: Liu, Hong-Bao, et al.
Publicado: (2015)

Notch1/Hes1-PTEN/AKT/IL-17A feedback loop regulates Th17 cell differentiation in mouse psoriasis-like skin inflammation
por: Lin, Ya-Wen, et al.
Publicado: (2022)

Patchouli alcohol protects against myocardial ischaemia–reperfusion injury by regulating the Notch1/Hes1 pathway
por: Lu, Ying, et al.
Publicado: (2022)

Acupuncture inhibits Notch1 and Hes1 protein expression in the basal ganglia of rats with cerebral hemorrhage
por: Zou, Wei, et al.
Publicado: (2015)

Melatonin ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by preserving mitochondrial function: role of AMPK-PGC-1α-SIRT3 signaling
por: Yu, Liming, et al.
Publicado: (2017)

Mechanism of N-acetylcysteine in alleviating diabetic myocardial ischemia reperfusion injury by regulating PTEN/Akt pathway through promoting DJ-1
por: Li, Wenyuan, et al.
Publicado: (2020)

HES-Mediated Repression of Pten in Caenorhabditis elegans
por: Chou, Han Ting, et al.
Publicado: (2015)

Hes1 promotes cell proliferation and migration by activating Bmi-1 and PTEN/Akt/GSK3β pathway in human colon cancer
por: Gao, Fei, et al.
Publicado: (2015)

Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3-FOXO1 signaling pathway
por: Jiang, Jian, et al.
Publicado: (2019)

Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3-FOXO1 signaling pathway
por: Jiang, Jian, et al.
Publicado: (2019)

The NOTCH-HES-1 axis is involved in promoting Th22 cell differentiation
por: Zeng, Chong, et al.
Publicado: (2021)

miR-194-5p protects against myocardial ischemia/reperfusion injury via MAPK1/PTEN/AKT pathway
por: Zhang, Qiufeng, et al.
Publicado: (2021)

HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development
por: De Decker, Matthias, et al.
Publicado: (2020)

Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury
por: Gao, Youguang, et al.
Publicado: (2016)

Hes1 triggers epithelial-mesenchymal transition (EMT)-like cellular marker alterations and promotes invasion and metastasis of nasopharyngeal carcinoma by activating the PTEN/AKT pathway
por: Wang, Sheng-Chun, et al.
Publicado: (2015)

Inhibiting ATP6V0D2 Aggravates Liver Ischemia-Reperfusion Injury by Promoting NLRP3 Activation via Impairing Autophagic Flux Independent of Notch1/Hes1
por: Wang, Ziyi, et al.
Publicado: (2021)

Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately
por: Shi, Yan, et al.
Publicado: (2015)

Sodium danshensu attenuates cerebral ischemia–reperfusion injury by targeting AKT1
por: Gao, Qing, et al.
Publicado: (2022)

Regulation of NOTCH Signaling by Reciprocal Inhibition of HES1 and Deltex 1 and its Role in Osteosarcoma Invasiveness
por: Zhang, Pingyu, et al.
Publicado: (2010)

Hes1 regulates embryonic stem cell differentiation by suppressing Notch signaling
por: Kobayashi, Taeko, et al.
Publicado: (2010)

The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt
por: Kay, Sophie K., et al.
Publicado: (2017)

MACF1 alleviates aging‐related osteoporosis via HES1
por: Yin, Chong, et al.
Publicado: (2021)

DAPT Attenuates Cadmium-Induced Toxicity in Mice by Inhibiting Inflammation and the Notch/HES-1 Signaling Axis
por: Yang, Jia-Ying, et al.
Publicado: (2022)

SPIONs enhances IL-10-producing macrophages to relieve sepsis via Cav1-Notch1/HES1-mediated autophagy
por: Xu, Yujun, et al.
Publicado: (2019)

Erratum to: Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately
por: Shi, Yan, et al.
Publicado: (2015)

Simulated microgravity hampers Notch signaling in the fight against myocardial ischemia-reperfusion injury
por: Jiang, Shuai, et al.
Publicado: (2018)

The AKT1/NF-kappaB/Notch1/PTEN axis has an important role in chemoresistance of gastric cancer cells
por: Zhou, W, et al.
Publicado: (2013)

Synthetic DNA-Binding Inhibitor of HES1 Alters the Notch Signaling Pathway and Induces Neuronal Differentiation
por: Wei, Yulei, et al.
Publicado: (2018)

Notch1 Protects against Ischemic-Reperfusion Injury by Suppressing PTEN-Pink1-Mediated Mitochondrial Dysfunction and Mitophagy
por: Xu, Qirong, et al.
Publicado: (2022)

MiR-195-5p Ameliorates Cerebral Ischemia-Reperfusion Injury by Regulating the PTEN-AKT Signaling Pathway
por: Ren, Xiaoli, et al.
Publicado: (2021)

Adipose-Derived Mesenchymal Stem Cell Facilitate Hematopoietic Stem Cell Proliferation via the Jagged-1/Notch-1/Hes Signaling Pathway
por: Wang, Hongbo, et al.
Publicado: (2023)

Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity
por: Wall, Dana S., et al.
Publicado: (2009)

Hes1 Potentiates T Cell Lymphomagenesis by Up-Regulating a Subset of Notch Target Genes
por: Dudley, Darryll D., et al.
Publicado: (2009)

Inhibition of MiR-122 Decreases Cerebral Ischemia-reperfusion Injury by Upregulating DJ-1-Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN)/Phosphonosinol-3 Kinase (PI3K)/AKT
por: Xue, XinHong, et al.
Publicado: (2020)

miR-129 Attenuates Myocardial Ischemia Reperfusion Injury by Regulating the Expression of PTEN in Rats
por: Dai, Zhao-Hui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gan3n6r8on2e4srpnpmqjpe93g