Redefining mouse transgenesis with CRISPR/Cas9 genome editing technology

The generation of genetically modified alleles in mice using conventional transgenesis technologies is a long and inefficient process. A new study shows that the in situ delivery of CRISPR/Cas9 reagents into pregnant mice results in a high efficiency of editing, and enables the rapid generation of b...

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Detalles Bibliográficos
Autor principal: Burgio, Gaetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831610/
https://www.ncbi.nlm.nih.gov/pubmed/29490686
http://dx.doi.org/10.1186/s13059-018-1409-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831610/
https://www.ncbi.nlm.nih.gov/pubmed/29490686
http://dx.doi.org/10.1186/s13059-018-1409-1

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