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PGRP-LD mediates A. stephensi vector competency by regulating homeostasis of microbiota-induced peritrophic matrix synthesis

Peptidoglycan recognition proteins (PGRPs) and commensal microbes mediate pathogen infection outcomes in insect disease vectors. Although PGRP-LD is retained in multiple vectors, its role in host defense remains elusive. Here we report that Anopheles stephensi PGRP-LD protects the vector from malari...

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Detalles Bibliográficos
Autores principales: Song, Xiumei, Wang, Mengfei, Dong, Li, Zhu, Huaimin, Wang, Jingwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831637/
https://www.ncbi.nlm.nih.gov/pubmed/29489896
http://dx.doi.org/10.1371/journal.ppat.1006899