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Optimizing homeostatic cell renewal in hierarchical tissues
In order to maintain homeostasis, mature cells removed from the top compartment of hierarchical tissues have to be replenished by means of differentiation and self-renewal events happening in the more primitive compartments. As each cell division is associated with a risk of mutation, cell division...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831642/ https://www.ncbi.nlm.nih.gov/pubmed/29447149 http://dx.doi.org/10.1371/journal.pcbi.1005967 |