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Brca2, Pds5 and Wapl differentially control cohesin chromosome association and function

The cohesin complex topologically encircles chromosomes and mediates sister chromatid cohesion to ensure accurate chromosome segregation upon cell division. Cohesin also participates in DNA repair and gene transcription. The Nipped-B–Mau2 protein complex loads cohesin onto chromosomes and the Pds5—W...

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Detalles Bibliográficos
Autores principales: Misulovin, Ziva, Pherson, Michelle, Gause, Maria, Dorsett, Dale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831647/
https://www.ncbi.nlm.nih.gov/pubmed/29447171
http://dx.doi.org/10.1371/journal.pgen.1007225