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Oil Palm Phenolics Inhibit the In Vitro Aggregation of β-Amyloid Peptide into Oligomeric Complexes

Alzheimer's disease is a severe neurodegenerative disease characterized by the aggregation of amyloid-β peptide (Aβ) into toxic oligomers which activate microglia and astrocytes causing acute neuroinflammation. Multiple studies show that the soluble oligomers of Aβ42 are neurotoxic and proinfla...

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Detalles Bibliográficos
Autores principales: Weinberg, Robert P., Koledova, Vera V., Shin, Hyeari, Park, Jennifer H., Tan, Yew Ai, Sinskey, Anthony J., Sambanthamurthi, Ravigadevi, Rha, ChoKyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831689/
https://www.ncbi.nlm.nih.gov/pubmed/29666700
http://dx.doi.org/10.1155/2018/7608038