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Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

BACKGROUND: Human mesenchymal stem cell (hMSC) differentiation into osteoblasts has important clinical significance in treating bone injury, and the stiffness of the extracellular matrix (ECM) has been shown to be an important regulatory factor for hMSC differentiation. The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Sun, Meiyu, Chi, Guangfan, Xu, Juanjuan, Tan, Ye, Xu, Jiayi, Lv, Shuang, Xu, Ziran, Xia, Yuhan, Li, Lisha, Li, Yulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831741/
https://www.ncbi.nlm.nih.gov/pubmed/29490668
http://dx.doi.org/10.1186/s13287-018-0798-0