Cargando…

Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

BACKGROUND: Human mesenchymal stem cell (hMSC) differentiation into osteoblasts has important clinical significance in treating bone injury, and the stiffness of the extracellular matrix (ECM) has been shown to be an important regulatory factor for hMSC differentiation. The aim of this study was to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Meiyu, Chi, Guangfan, Xu, Juanjuan, Tan, Ye, Xu, Jiayi, Lv, Shuang, Xu, Ziran, Xia, Yuhan, Li, Lisha, Li, Yulin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831741/ https://www.ncbi.nlm.nih.gov/pubmed/29490668 http://dx.doi.org/10.1186/s13287-018-0798-0

Ejemplares similares

Effects of Matrix Stiffness on the Morphology, Adhesion, Proliferation and Osteogenic Differentiation of Mesenchymal Stem Cells
por: Sun, Meiyu, et al.
Publicado: (2018)

Soft Matrix Combined With BMPR Inhibition Regulates Neurogenic Differentiation of Human Umbilical Cord Mesenchymal Stem Cells
por: Sun, Yingying, et al.
Publicado: (2020)

Matrix stiffness regulates myocardial differentiation of human umbilical cord mesenchymal stem cells
por: Sun, Yingying, et al.
Publicado: (2020)

Efficient feeder cells preparation system for large-scale preparation and application of induced pluripotent stem cells
por: Li, Pengdong, et al.
Publicado: (2017)

Mechanism of regulation of stem cell differentiation by matrix stiffness
por: Lv, Hongwei, et al.
Publicado: (2015)

Extracellular matrix stiffness dictates Wnt expression through integrin pathway
por: Du, Jing, et al.
Publicado: (2016)

Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation
por: Hwang, Jun-Ha, et al.
Publicado: (2015)

Exosomes derived from umbilical cord mesenchymal stem cells protect cartilage and regulate the polarization of macrophages in osteoarthritis
por: Li, Pengdong, et al.
Publicado: (2022)

Extramedullary Osseointegration—A Novel Design of Percutaneous Osseointegration Prosthesis for Amputees
por: Sun, Yingying, et al.
Publicado: (2022)

Rat vibrissa dermal papilla cells promote healing of spinal cord injury following transplantation
por: Li, Meiying, et al.
Publicado: (2018)

Chromatin remodeling and nucleoskeleton synergistically control osteogenic differentiation in different matrix stiffnesses
por: Xu, Xinxin, et al.
Publicado: (2023)

Effect of Polymeric Matrix Stiffness on Osteogenic Differentiation of Mesenchymal Stem/Progenitor Cells: Concise Review
por: El-Rashidy, Aiah A., et al.
Publicado: (2021)

Extracellular matrix stiffness—The central cue for skin fibrosis
por: Wang, Kang, et al.
Publicado: (2023)

MicroRNA-27b targets CBFB to inhibit differentiation of human bone marrow mesenchymal stem cells into hypertrophic chondrocytes
por: Lv, Shuang, et al.
Publicado: (2020)

Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation
por: Zhu, Tong, et al.
Publicado: (2023)

Biological characteristics of side population cells in a self-established human ovarian cancer cell line
por: WEI, ZHENTONG, et al.
Publicado: (2016)

Impact of Donor Age on the Osteogenic Supportive Capacity of Mesenchymal Stromal Cell-Derived Extracellular Matrix
por: Carvalho, Marta S., et al.
Publicado: (2021)

miR-27b promotes type II collagen expression by targetting peroxisome proliferator-activated receptor-γ2 during rat articular chondrocyte differentiation
por: Xu, Jinying, et al.
Publicado: (2018)

Organ sculpting by patterned extracellular matrix stiffness
por: Crest, Justin, et al.
Publicado: (2017)

Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells
por: Li, Meiying, et al.
Publicado: (2014)

Extracellular matrix alters PDGF regulation of fibroblast integrins
Publicado: (1996)

Extracellular Matrix and Integrins in Embryonic Stem Cell Differentiation
por: Wang, Han, et al.
Publicado: (2015)

Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration
por: Motoike, Souta, et al.
Publicado: (2018)

Stiff Extracellular Matrix Promotes Invasive Behaviors of Trophoblast Cells
por: Cao, Jialing, et al.
Publicado: (2023)

Overexpression of long non-coding RNA AP001505.9 inhibits human hyaline chondrocyte dedifferentiation
por: Chen, Lin, et al.
Publicado: (2021)

Regulation of integrin and extracellular matrix genes by HNRNPL is necessary for epidermal renewal
por: Li, Jingting, et al.
Publicado: (2021)

Interactions of the Mechanosensitive Channels with Extracellular Matrix, Integrins, and Cytoskeletal Network in Osmosensation
por: Jiao, Runsheng, et al.
Publicado: (2017)

Analysis of differentially expressed genes among human hair follicle–derived iPSCs, induced hepatocyte-like cells, and primary hepatocytes
por: Xu, Ziran, et al.
Publicado: (2018)

Synthetic osteogenic extracellular matrix formed by coated silicon dioxide nanosprings
por: Hass, Jamie L, et al.
Publicado: (2012)

Differentiated osteoblasts derived decellularized extracellular matrix to promote osteogenic differentiation
por: Jeon, Jin, et al.
Publicado: (2018)

Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis
por: Chen, Jie, et al.
Publicado: (2012)

Integrins and extracellular matrix proteins modulate adipocyte thermogenic capacity
por: Gonzalez Porras, Maria A., et al.
Publicado: (2021)

Stiffness of the Extracellular Matrix: A Regulator of Prostaglandins in Pulmonary Fibrosis?
por: Jandl, Katharina, et al.
Publicado: (2020)

Extracellular Matrix Stiffness: New Areas Affecting Cell Metabolism
por: Ge, Heming, et al.
Publicado: (2021)

Targeting extracellular matrix stiffness and mechanotransducers to improve cancer therapy
por: Jiang, Yangfu, et al.
Publicado: (2022)

Evaluation of an Autologous Bone Mesenchymal Stem Cell-Derived Extracellular Matrix Scaffold in a Rabbit and Minipig Model of Cartilage Repair
por: Tang, Cheng, et al.
Publicado: (2019)

ASPN Synergizes with HAPLN1 to Inhibit the Osteogenic Differentiation of Bone Marrow Mesenchymal Stromal Cells and Extracellular Matrix Mineralization of Osteoblasts
por: Zhou, Guohui, et al.
Publicado: (2023)

Integrated PPI- and WGCNA-retrieval of hub gene signatures for soft substrates inhibition of human fibroblasts proliferation and differentiation
por: Xu, Ziran, et al.
Publicado: (2022)

A Theoretical Approach to Coupling the Epithelial-Mesenchymal Transition (EMT) to Extracellular Matrix (ECM) Stiffness via LOXL2
por: Deng, Youyuan, et al.
Publicado: (2021)

Modeling the Kinetics of Integrin Receptor Binding to Hepatic Extracellular Matrix Proteins
por: Hudson, Shanice V., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ssa13tov87ghv2eolj28a9k9m2