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A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

Host restriction factors constitute a formidable barrier for viral replication to which many viruses have evolved counter-measures. Human SAMD9, a tumor suppressor and a restriction factor for poxviruses in cell lines, is antagonized by two classes of poxvirus proteins, represented by vaccinia virus...

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Detalles Bibliográficos
Autores principales: Meng, Xiangzhi, Zhang, Fushun, Yan, Bo, Si, Chuanping, Honda, Hiroaki, Nagamachi, Akiko, Sun, Lu-Zhe, Xiang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831749/
https://www.ncbi.nlm.nih.gov/pubmed/29447249
http://dx.doi.org/10.1371/journal.ppat.1006884