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A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection
Host restriction factors constitute a formidable barrier for viral replication to which many viruses have evolved counter-measures. Human SAMD9, a tumor suppressor and a restriction factor for poxviruses in cell lines, is antagonized by two classes of poxvirus proteins, represented by vaccinia virus...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831749/ https://www.ncbi.nlm.nih.gov/pubmed/29447249 http://dx.doi.org/10.1371/journal.ppat.1006884 |