Murine cytomegalovirus degrades MHC class II to colonize the salivary glands

Cytomegaloviruses (CMVs) persistently and systemically infect the myeloid cells of immunocompetent hosts. Persistence implies immune evasion, and CMVs evade CD8(+) T cells by inhibiting MHC class I-restricted antigen presentation. Myeloid cells can also interact with CD4(+) T cells via MHC class II...

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Detalles Bibliográficos
Autores principales: Yunis, Joseph, Farrell, Helen E., Bruce, Kimberley, Lawler, Clara, Sidenius, Stine, Wyer, Orry, Davis-Poynter, Nicholas, Stevenson, Philip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831752/
https://www.ncbi.nlm.nih.gov/pubmed/29447285
http://dx.doi.org/10.1371/journal.ppat.1006905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831752/
https://www.ncbi.nlm.nih.gov/pubmed/29447285
http://dx.doi.org/10.1371/journal.ppat.1006905

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