Creating a more robust 5-hydroxymethylfurfural oxidase by combining computational predictions with a novel effective library design

BACKGROUND: HMF oxidase (HMFO) from Methylovorus sp. is a recently characterized flavoprotein oxidase. HMFO is a remarkable enzyme as it is able to oxidize 5-hydroxymethylfurfural (HMF) into 2,5-furandicarboxylic acid (FDCA): a catalytic cascade of three oxidation steps. Because HMF can be formed fr...

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Detalles Bibliográficos
Autores principales: Martin, Caterina, Ovalle Maqueo, Amaury, Wijma, Hein J., Fraaije, Marco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831843/
https://www.ncbi.nlm.nih.gov/pubmed/29507608
http://dx.doi.org/10.1186/s13068-018-1051-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831843/
https://www.ncbi.nlm.nih.gov/pubmed/29507608
http://dx.doi.org/10.1186/s13068-018-1051-x

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