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Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimer’s disease

Although the genetic causes for several rare, familial forms of Alzheimer’s disease (AD) have been identified, the etiology of the sporadic form of AD remains unclear. Here, we report a systems-level study of disease-associated proteome changes in human frontal cortex of sporadic AD patients using a...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Ma, Cheng, Gearing, Marla, Wang, Peng George, Chin, Lih-Shen, Li, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831854/
https://www.ncbi.nlm.nih.gov/pubmed/29490708
http://dx.doi.org/10.1186/s40478-018-0524-2