A Novel Mechanism of Mesenchymal Stromal Cell-Mediated Protection against Sepsis: Restricting Inflammasome Activation in Macrophages by Increasing Mitophagy and Decreasing Mitochondrial ROS

Sepsis, a systemic inflammatory response to infection, is the leading cause of death in the intensive care unit (ICU). Previous studies indicated that mesenchymal stromal cells (MSCs) might have therapeutic potential against sepsis. The current study was designed to investigate the effects of MSCs o...

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Detalles Bibliográficos
Autores principales: Li, Shuang, Wu, Hao, Han, Dong, Ma, Sai, Fan, Wensi, Wang, Yabin, Zhang, Ran, Fan, Miaomiao, Huang, Yuesheng, Fu, Xiaobing, Cao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831900/
https://www.ncbi.nlm.nih.gov/pubmed/29636842
http://dx.doi.org/10.1155/2018/3537609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831900/
https://www.ncbi.nlm.nih.gov/pubmed/29636842
http://dx.doi.org/10.1155/2018/3537609

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