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Betulinic Acid-Mediated Apoptosis in Human Prostate Cancer Cells Involves p53 and Nuclear Factor-Kappa B (NF-κB) Pathways

Defects in p53 and nuclear factor-kappa B (NF-κB) signaling pathways are frequently observed in the initiation and development of various human malignancies, including prostate cancer. Clinical studies demonstrate higher expression of NF-κB/p65/RelA, NF-κB/p50/RelB, and cRel as well as downregulatio...

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Detalles Bibliográficos
Autores principales: Shankar, Eswar, Zhang, Ailin, Franco, Daniel, Gupta, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832059/
https://www.ncbi.nlm.nih.gov/pubmed/28208611
http://dx.doi.org/10.3390/molecules22020264