Cargando…

highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models

Rhodopsins require retinoid chromophores for their function. In vertebrates, retinoids also serve as signaling molecules, but whether these molecules similarly regulate gene expression in Drosophila remains unclear. Here, we report the identification of a retinoid-inducible gene in Drosophila, highr...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Huai-Wei, Brown, Brian, Chung, Jaehoon, Domingos, Pedro M., Ryoo, Hyung Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832065/
https://www.ncbi.nlm.nih.gov/pubmed/29425495
http://dx.doi.org/10.1016/j.celrep.2018.01.032