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PKM2 Is Required to Activate Myeloid Dendritic Cells from Patients with Severe Aplastic Anemia

Severe aplastic anemia (SAA) is an autoimmune disease in which bone marrow failure is mediated by activated myeloid dendritic cells (mDCs) and T lymphocytes. Recent research has identified a strong immunomodulatory effect of pyruvate kinase M2 (PKM2) on dendritic cells in immune-mediated diseases. I...

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Detalles Bibliográficos
Autores principales:	Liu, Chunyan, Zheng, Mengying, Wang, Ting, Jiang, Huijuan, Fu, Rong, Wang, Huaquan, Ding, Kai, Zhou, Qiufan, Shao, Zonghong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832124/ https://www.ncbi.nlm.nih.gov/pubmed/29636835 http://dx.doi.org/10.1155/2018/1364165

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