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Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes

The skin covers the outer surface of the body, so the epidermal keratinocytes within it are susceptible to reactive oxygen species (ROS) generated by environmental pollutants such as benzo(a)pyrene (BaP), a potent activator of aryl hydrocarbon receptor (AHR). Antioxidant activity is generally mediat...

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Detalles Bibliográficos
Autores principales: Fuyuno, Yoko, Uchi, Hiroshi, Yasumatsu, Mao, Morino-Koga, Saori, Tanaka, Yuka, Mitoma, Chikage, Furue, Masutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832143/
https://www.ncbi.nlm.nih.gov/pubmed/29643980
http://dx.doi.org/10.1155/2018/9524657