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Lipopolysaccharide-binding protein (LBP) can reverse the amyloid state of fibrin seen or induced in Parkinson's disease

The thrombin-induced polymerisation of fibrinogen to form fibrin is well established as a late stage of blood clotting. It is known that Parkinson’s Disease (PD) is accompanied by dysregulation in blood clotting, but it is less widely known as a coagulopathy. In recent work, we showed that the prese...

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Detalles Bibliográficos
Autores principales: Pretorius, Etheresia, Page, Martin J., Mbotwe, Sthembile, Kell, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832207/
https://www.ncbi.nlm.nih.gov/pubmed/29494603
http://dx.doi.org/10.1371/journal.pone.0192121