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Computational de novo discovery of distinguishing genes for biological processes and cell types in complex tissues
Bulk tissue samples examined by gene expression studies are usually heterogeneous. The data gained from these samples display the confounding patterns of mixtures consisting of multiple cell types or similar cell types in various functional states, which hinders the elucidation of the molecular mech...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832224/ https://www.ncbi.nlm.nih.gov/pubmed/29494600 http://dx.doi.org/10.1371/journal.pone.0193067 |