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The importance of negative determinants as modulators of CK2 targeting. The lesson of Akt2 S131

CK2 is a pleiotropic S/T protein kinase (formerly known as casein kinase 2) which is attracting increasing interest as therapeutic target, and the identification of its substrates is a crucial step in determining its involvement in different pathological conditions. We recently found that S131 of Ak...

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Detalles Bibliográficos
Autores principales: Vilardell, Jordi, Girardi, Cristina, Marin, Oriano, Cozza, Giorgio, Pinna, Lorenzo A., Ruzzene, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832243/
https://www.ncbi.nlm.nih.gov/pubmed/29494643
http://dx.doi.org/10.1371/journal.pone.0193479