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IL-12/23p40 overproduction by dendritic cells leads to an increased Th1 and Th17 polarization in a model of Yersinia enterocolitica-induced reactive arthritis in TNFRp55(-/-) mice

Dendritic cells (DCs) play critical functions in the initiation of immune responses. Understanding their role in reactive arthritis (ReA) will help delineate the pathogenesis of this arthropathy. In early studies, we detected IL-12/23p40 deregulation in Yersinia entercolitica (Ye)-induced ReA in TNF...

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Detalles Bibliográficos
Autores principales: Mayordomo, Andrea Constanza, Silva, Juan Eduardo, Gorlino, Carolina Virginia, Arias, José Luis, Berón, Walter, Di Genaro, María Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832265/
https://www.ncbi.nlm.nih.gov/pubmed/29494692
http://dx.doi.org/10.1371/journal.pone.0193573