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Combined effect of glutamine at position 70 of HLA-DRB1 and alanine at position 57 of HLA-DQB1 in type 1 diabetes: An epitope analysis

The contribution of specific HLA Class II alleles in type 1 diabetes is determined by polymorphic amino acid epitopes that direct antigen binding therefore, along with conventional allele frequency analysis, epitope analysis can provide important insights into disease susceptibility. We analyzed the...

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Detalles Bibliográficos
Autores principales: Gerasimou, Petroula, Nicolaidou, Vicky, Skordis, Nicos, Picolos, Michalis, Monos, Demetrios, Costeas, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832312/
https://www.ncbi.nlm.nih.gov/pubmed/29494662
http://dx.doi.org/10.1371/journal.pone.0193684