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Lysine methyltransferase SMYD2 promotes triple negative breast cancer progression

We identified SMYD2, a SMYD (SET and MYND domain) family protein with lysine methyltransferase activity, as a novel breast cancer oncogene. SMYD2 was expressed at significantly higher levels in breast cancer cell lines and in breast tumor tissues. Silencing of SMYD2 by RNAi in triple-negative breast...

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Detalles Bibliográficos
Autores principales: Li, Linda Xiaoyan, Zhou, Julie Xia, Calvet, James P., Godwin, Andrew K., Jensen, Roy A., Li, Xiaogang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832424/
https://www.ncbi.nlm.nih.gov/pubmed/29487338
http://dx.doi.org/10.1038/s41419-018-0347-x