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Disruption of ER−mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis

Fronto-temporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two related and incurable neurodegenerative diseases. Features of these diseases include pathological protein inclusions in affected neurons with TAR DNA-binding protein 43 (TDP-43), dipeptide repeat proteins derived from the...

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Detalles Bibliográficos
Autores principales: Lau, Dawn H. W., Hartopp, Naomi, Welsh, Natalie J., Mueller, Sarah, Glennon, Elizabeth B., Mórotz, Gábor M., Annibali, Ambra, Gomez-Suaga, Patricia, Stoica, Radu, Paillusson, Sebastien, Miller, Christopher C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832427/
https://www.ncbi.nlm.nih.gov/pubmed/29491392
http://dx.doi.org/10.1038/s41419-017-0022-7