Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder

Alcohol Use Disorder (AUD) is a common and chronic disorder with substantial effects on personal and public health(1). The underlying pathophysiology is poorly understood but strong evidence suggests significant roles of both genetic and epigenetic components(2). Given that alcohol affects many orga...

Descripción completa

Detalles Bibliográficos
Autores principales: Lohoff, Falk W., Sorcher, Jill L., Rosen, Allison D., Mauro, Kelsey L., Fanelli, Rebecca R., Momenan, Reza, Hodgkinson, Colin A., Vendruscolo, Leandro F., Koob, George F., Schwandt, Melanie, George, David T., Jones, Ilenna S., Holmes, Andrew, Zhou, Zhou, Xu, Ming-Jiang, Gao, Bin, Sun, Hui, Phillips, Monte J., Muench, Christine, Kaminsky, Zachary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832488/
https://www.ncbi.nlm.nih.gov/pubmed/28848234
http://dx.doi.org/10.1038/mp.2017.168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832488/
https://www.ncbi.nlm.nih.gov/pubmed/28848234
http://dx.doi.org/10.1038/mp.2017.168

Ejemplares similares