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Deguelin, an Aurora B Kinase Inhibitor, Exhibits Potent Anti-Tumor Effect in Human Esophageal Squamous Cell Carcinoma

Aurora B kinase has emerged as a key regulator of mitosis and deregulation of Aurora B activity is closely related to the development and progression of human cancers. In the present study, we found that Aurora B is overexpressed in human esophageal squamous cell carcinoma (ESCC), high levels of Aur...

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Detalles Bibliográficos
Autores principales: Yu, Xinfang, Liang, Qi, Liu, Wenbin, Zhou, Li, Li, Wei, Liu, Haidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832566/
https://www.ncbi.nlm.nih.gov/pubmed/29129699
http://dx.doi.org/10.1016/j.ebiom.2017.10.030