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Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell–derived hepatocytes

Knowledge of activation and interplay between the hepatitis C virus (HCV) and the hosts’ innate immunity is essential to understanding the establishment of chronic HCV infection. Human hepatoma cell lines, widely used as HCV cell culture system, display numerous metabolic alterations and a defective...

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Detalles Bibliográficos
Autores principales: Schöbel, Anja, Rösch, Kathrin, Herker, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832748/
https://www.ncbi.nlm.nih.gov/pubmed/29497123
http://dx.doi.org/10.1038/s41598-018-22243-7