Cargando…

Functional innate immunity restricts Hepatitis C Virus infection in induced pluripotent stem cell–derived hepatocytes

Knowledge of activation and interplay between the hepatitis C virus (HCV) and the hosts’ innate immunity is essential to understanding the establishment of chronic HCV infection. Human hepatoma cell lines, widely used as HCV cell culture system, display numerous metabolic alterations and a defective...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schöbel, Anja, Rösch, Kathrin, Herker, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832748/ https://www.ncbi.nlm.nih.gov/pubmed/29497123 http://dx.doi.org/10.1038/s41598-018-22243-7

Ejemplares similares

Hepatitis C virus infection restricts human LINE-1 retrotransposition in hepatoma cells
por: Schöbel, Anja, et al.
Publicado: (2021)

Visualization and Analysis of Hepatitis C Virus Structural Proteins at Lipid Droplets by Super-Resolution Microscopy
por: Eggert, Dennis, et al.
Publicado: (2014)

Asunaprevir Evokes Hepatocytes Innate Immunity to Restrict the Replication of Hepatitis C and Dengue Virus
por: Tsai, Wei-Lun, et al.
Publicado: (2017)

Modulating Innate Immunity Improves Hepatitis C Virus Infection and Replication in Stem Cell-Derived Hepatocytes
por: Zhou, Xiaoling, et al.
Publicado: (2014)

Whole Lotta Lipids—From HCV RNA Replication to the Mature Viral Particle
por: Bley, Hanna, et al.
Publicado: (2020)

Modeling human hepatic steatosis in pluripotent stem cell-derived hepatocytes
por: Sinton, Matthew C., et al.
Publicado: (2021)

Pluripotent-Stem-Cell-Derived Hepatic Cells: Hepatocytes and Organoids for Liver Therapy and Regeneration
por: Messina, Antonietta, et al.
Publicado: (2020)

Modeling Dengue Virus-Hepatic Cell Interactions Using Human Pluripotent Stem Cell-Derived Hepatocyte-like Cells
por: Lang, Jianshe, et al.
Publicado: (2016)

Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection
por: Sakurai, Fuminori, et al.
Publicado: (2017)

Innate Host Response in Primary Human Hepatocytes with Hepatitis C Virus Infection
por: Yang, Darong, et al.
Publicado: (2011)

Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes
por: Verrier, Eloi R., et al.
Publicado: (2016)

Innate immune responses in human hepatocyte-derived cell lines alter genotype 1 hepatitis E virus replication efficiencies
por: Devhare, Pradip B., et al.
Publicado: (2016)

Efficient acute and chronic infection of stem cell-derived hepatocytes by hepatitis C virus
por: Carpentier, Arnaud, et al.
Publicado: (2020)

Maturation of Induced Pluripotent Stem Cell Derived Hepatocytes by 3D-Culture
por: Gieseck III, Richard L., et al.
Publicado: (2014)

Enrichment of Pluripotent Stem Cell-Derived Hepatocyte-Like Cells by Ammonia Treatment
por: Tomotsune, Daihachiro, et al.
Publicado: (2016)

Pluripotent Stem Cell-Derived Hepatocyte-like Cells: Induction Methods and Applications
por: Luo, Qiulin, et al.
Publicado: (2023)

An in vitro model of hepatic steatosis using lipid loaded induced pluripotent stem cell derived hepatocyte like cells
por: Deepak, Hiraganahalli Bhaskar, et al.
Publicado: (2020)

(−)-Epigallocatechin-3-Gallate Enhances Hepatitis C Virus Double-Stranded RNA Intermediates-Triggered Innate Immune Responses in Hepatocytes
por: Wang, Yizhong, et al.
Publicado: (2016)

ULBP1 is induced by hepatitis C virus infection and is the target of the NK cell‐mediated innate immune response in human hepatocytes
por: Dansako, Hiromichi, et al.
Publicado: (2018)

Successful Derivation of Hepatoblasts, Cholangiocytes and Hepatocytes from Simian Induced Pluripotent Stem Cells
por: Luce, Eleanor, et al.
Publicado: (2022)

The Interactions Between HBV and the Innate Immunity of Hepatocytes
por: Megahed, Fayed Attia Koutb, et al.
Publicado: (2020)

A Chimeric Humanized Mouse Model by Engrafting the Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cell for the Chronic Hepatitis B Virus Infection
por: Yuan, Lunzhi, et al.
Publicado: (2018)

Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus–Infected Hepatocytes During Interferon Administration
por: Fukutomi, Keisuke, et al.
Publicado: (2021)

Hepatitis C Virus: Evading the Intracellular Innate Immunity
por: Ferreira, Ana Rita, et al.
Publicado: (2020)

Hepatitis C virus entry into the hepatocyte
por: Belouzard, Sandrine, et al.
Publicado: (2011)

Bioprinting of a Hepatic Tissue Model Using Human-Induced Pluripotent Stem Cell-derived Hepatocytes for Drug-Induced Hepatotoxicity Evaluation
por: He, Jianyu, et al.
Publicado: (2022)

Blocking GSDMD processing in innate immune cells but not in hepatocytes protects hepatic ischemia–reperfusion injury
por: Li, Jichang, et al.
Publicado: (2020)

Characterisation of human induced pluripotent stem cell-derived hepatocyte-like cells and endodermal progenitors
por: Matz, Peggy, et al.
Publicado: (2014)

Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering
por: Lucendo-Villarin, B., et al.
Publicado: (2016)

Human Pluripotent Stem Cell-Derived Hepatocyte-Like Cells and Organoids for Liver Disease and Therapy
por: Li, Yang, et al.
Publicado: (2021)

Pluripotent Stem Cell-Derived Hepatocytes Inhibit T Cell Proliferation In Vitro through Tryptophan Starvation
por: Romano, Marco, et al.
Publicado: (2021)

Transmembrane channel activity in human hepatocytes and cholangiocytes derived from induced pluripotent stem cells
por: Florentino, Rodrigo M., et al.
Publicado: (2022)

The Innate Immune Playbook for Restricting West Nile Virus Infection
por: Quicke, Kendra M., et al.
Publicado: (2013)

Decellularized Organ-Derived Scaffold Is a Promising Carrier for Human Induced Pluripotent Stem Cells-Derived Hepatocytes
por: Kojima, Hideaki, et al.
Publicado: (2022)

Hepatocytes: a key cell type for innate immunity
por: Zhou, Zhou, et al.
Publicado: (2016)

Generation of human hepatocytes from extended pluripotent stem cells
por: Wang, Qiming, et al.
Publicado: (2020)

The Role of Humoral Innate Immunity in Hepatitis C Virus Infection
por: Tarr, Alexander W., et al.
Publicado: (2012)

Regulated Entry of Hepatitis C Virus into Hepatocytes
por: Miao, Zhijiang, et al.
Publicado: (2017)

Amelioration of Hyperbilirubinemia in Gunn Rats after Transplantation of Human Induced Pluripotent Stem Cell-Derived Hepatocytes
por: Chen, Yong, et al.
Publicado: (2015)

High-Content Assay Multiplexing for Toxicity Screening in Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Hepatocytes
por: Grimm, Fabian Alexander, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_9c0pi24medtdhh0ghc7v8hqgc8