Inhibition of FASN and ERα signalling during hyperglycaemia-induced matrix-specific EMT promotes breast cancer cell invasion via a caveolin-1-dependent mechanism

Since disturbed metabolic conditions such as obesity and diabetes can be critical determinants of breast cancer progression and therapeutic failure, we aimed to determine the mechanism responsible for their pro-oncogenic effects. Using non-invasive, epithelial-like ERα-positive MCF-7 and T47D human...

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Detalles Bibliográficos
Autores principales: Zielinska, H.A., Holly, J.M.P., Bahl, A., Perks, C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832758/
https://www.ncbi.nlm.nih.gov/pubmed/29331414
http://dx.doi.org/10.1016/j.canlet.2018.01.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832758/
https://www.ncbi.nlm.nih.gov/pubmed/29331414
http://dx.doi.org/10.1016/j.canlet.2018.01.028

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