Engineering Axl specific CAR and SynNotch receptor for cancer therapy

Axl is a tyrosine kinase receptor that is commonly overexpressed in many cancers. As such, Axl represents an attractive therapeutic target. The transfer of engineered T cell expressing chimeric antigen receptor (CAR) is an exciting cancer therapeutic approach that shows high efficacy against cancers...

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Detalles Bibliográficos
Autores principales: Cho, Jang Hwan, Okuma, Atsushi, Al-Rubaye, Dalal, Intisar, Ejaj, Junghans, Richard P., Wong, Wilson W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832765/
https://www.ncbi.nlm.nih.gov/pubmed/29497107
http://dx.doi.org/10.1038/s41598-018-22252-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832765/
https://www.ncbi.nlm.nih.gov/pubmed/29497107
http://dx.doi.org/10.1038/s41598-018-22252-6

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