De novo adipocyte differentiation from Pdgfrβ(+) preadipocytes protects against pathologic visceral adipose expansion in obesity

Pathologic expansion of white adipose tissue (WAT) in obesity is characterized by adipocyte hypertrophy, inflammation, and fibrosis; however, factors triggering this maladaptive remodeling are largely unknown. Here, we test the hypothesis that the potential to recruit new adipocytes from Pdgfrβ(+) p...

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Detalles Bibliográficos
Autores principales: Shao, Mengle, Vishvanath, Lavanya, Busbuso, Napoleon C., Hepler, Chelsea, Shan, Bo, Sharma, Ankit X., Chen, Shiuhwei, Yu, Xinxin, An, Yu A., Zhu, Yi, Holland, William L., Gupta, Rana K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832777/
https://www.ncbi.nlm.nih.gov/pubmed/29497032
http://dx.doi.org/10.1038/s41467-018-03196-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832777/
https://www.ncbi.nlm.nih.gov/pubmed/29497032
http://dx.doi.org/10.1038/s41467-018-03196-x

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