A preliminary study on efficacy of rupatadine for the treatment of acute dengue infection

Currently there are no specific treatments available for acute dengue infection. We considered that rupatadine, a platelet-activating factor receptor inhibitor, might modulate dengue-associated vascular leak. The effects of rupatadine were assessed in vitro, and in a dengue model, which showed that...

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Detalles Bibliográficos
Autores principales: Malavige, Gathsaurie Neelika, Wijewickrama, Ananda, Fernando, Samitha, Jeewandara, Chandima, Ginneliya, Anushka, Samarasekara, Supun, Madushanka, Praveen, Punchihewa, Chameera, Paranavitane, Shiran, Idampitiya, Damayanthi, Wanigatunga, Chandanie, Dissanayake, Harsha, Prathapan, Shamini, Gomes, Laksiri, Aman, Siti A. B., John, Ashley St., Ogg, Graham S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832788/
https://www.ncbi.nlm.nih.gov/pubmed/29497121
http://dx.doi.org/10.1038/s41598-018-22285-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832788/
https://www.ncbi.nlm.nih.gov/pubmed/29497121
http://dx.doi.org/10.1038/s41598-018-22285-x

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