Tolerance of chronic HDACi treatment for neurological, visceral and lung Niemann-Pick Type C disease in mice

Histone deacetylase (HDAC) inhibitors are of significant interest as drugs. However, their use to treat neurological disorders has raised concern because HDACs are required for brain function. We have previously shown that a triple combination formulation (TCF) of the pan HDACi vorinostat (Vo), 2-hy...

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Detalles Bibliográficos
Autores principales: Alam, Md. Suhail, Cooper, Bruce, Farris, Joseph D., Haldar, Kasturi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832807/
https://www.ncbi.nlm.nih.gov/pubmed/29497113
http://dx.doi.org/10.1038/s41598-018-22162-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832807/
https://www.ncbi.nlm.nih.gov/pubmed/29497113
http://dx.doi.org/10.1038/s41598-018-22162-7

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