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Genetic variants in two pathways influence serum urate levels and gout risk: a systematic pathway analysis

The aims of this study were to identify candidate pathways associated with serum urate and to explore the genetic effect of those pathways on the risk of gout. Pathway analysis of the loci identified in genome-wide association studies (GWASs) showed that the ion transmembrane transporter activity pa...

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Detalles Bibliográficos
Autores principales: Dong, Zheng, Zhou, Jingru, Xu, Xia, Jiang, Shuai, Li, Yuan, Zhao, Dongbao, Yang, Chengde, Ma, Yanyun, Wang, Yi, He, Hongjun, Ji, Hengdong, Zhang, Juan, Yuan, Ziyu, Yang, Yajun, Wang, Xiaofeng, Pang, Yafei, Jin, Li, Zou, Hejian, Wang, Jiucun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832812/
https://www.ncbi.nlm.nih.gov/pubmed/29497127
http://dx.doi.org/10.1038/s41598-018-21858-0