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An allosteric link connecting the lipid-protein interface to the gating of the nicotinic acetylcholine receptor
The mechanisms underlying lipid-sensing by membrane proteins is of considerable biological importance. A unifying mechanistic question is how a change in structure at the lipid-protein interface is translated through the transmembrane domain to influence structures critical to protein function. Gati...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832824/ https://www.ncbi.nlm.nih.gov/pubmed/29497086 http://dx.doi.org/10.1038/s41598-018-22150-x |