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Critical role of sigma-1 receptors in central neuropathic pain-related behaviours after mild spinal cord injury in mice

Sigma-1 receptor (σ(1)R) knockout (KO) CD1 mice, generated by homologous recombination, and separate pharmacological studies in wild type (WT) mice were done to investigate the role of this receptor in the development of pain-related behaviours (thermal hyperalgesia and mechanical allodynia) in mice...

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Detalles Bibliográficos
Autores principales: Castany, Sílvia, Gris, Georgia, Vela, José Miguel, Verdú, Enrique, Boadas-Vaello, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832850/
https://www.ncbi.nlm.nih.gov/pubmed/29497125
http://dx.doi.org/10.1038/s41598-018-22217-9