Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) protein that can be secreted and protects dopamine neurons and cardiomyocytes from ER stress and apoptosis. The mechanism of action of extracellular MANF has long been elusive. From a genetic screen for mutan...

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Detalles Bibliográficos
Autores principales: Bai, Meirong, Vozdek, Roman, Hnízda, Aleš, Jiang, Chenxiao, Wang, Bingying, Kuchar, Ladislav, Li, Tiejun, Zhang, Yuefan, Wood, Chase, Feng, Liang, Dang, Yongjun, Ma, Dengke K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832864/
https://www.ncbi.nlm.nih.gov/pubmed/29497057
http://dx.doi.org/10.1038/s41467-018-03355-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832864/
https://www.ncbi.nlm.nih.gov/pubmed/29497057
http://dx.doi.org/10.1038/s41467-018-03355-0

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