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Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs)

Fibroblasts can be directly reprogrammed to induced renal tubular epithelial cells (iRECs) using four transcription factors. These engineered cells may be used for disease modeling, cell replacement therapy or drug and toxicity testing. Direct reprogramming induces drastic changes in the transcripti...

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Detalles Bibliográficos
Autores principales: Lagies, Simon, Pichler, Roman, Kaminski, Michael M., Schlimpert, Manuel, Walz, Gerd, Lienkamp, Soeren S., Kammerer, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832874/
https://www.ncbi.nlm.nih.gov/pubmed/29497074
http://dx.doi.org/10.1038/s41598-018-22073-7