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Metabolic characterization of directly reprogrammed renal tubular epithelial cells (iRECs)
Fibroblasts can be directly reprogrammed to induced renal tubular epithelial cells (iRECs) using four transcription factors. These engineered cells may be used for disease modeling, cell replacement therapy or drug and toxicity testing. Direct reprogramming induces drastic changes in the transcripti...
Autores principales: | Lagies, Simon, Pichler, Roman, Kaminski, Michael M., Schlimpert, Manuel, Walz, Gerd, Lienkamp, Soeren S., Kammerer, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832874/ https://www.ncbi.nlm.nih.gov/pubmed/29497074 http://dx.doi.org/10.1038/s41598-018-22073-7 |
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