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Analysis of HETEs in human whole blood by chiral UHPLC-ECAPCI/HRMS

The biosynthesis of eicosanoids occurs enzymatically via lipoxygenases, cyclooxygenases, and cytochrome P450, or through nonenzymatic free radical reactions. The enzymatic routes are highly enantiospecific. Chiral separation and high-sensitivity detection methods are required to differentiate and qu...

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Detalles Bibliográficos
Autores principales: Mazaleuskaya, Liudmila L., Salamatipour, Ashkan, Sarantopoulou, Dimitra, Weng, Liwei, FitzGerald, Garret A., Blair, Ian A., Mesaros, Clementina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832923/
https://www.ncbi.nlm.nih.gov/pubmed/29301865
http://dx.doi.org/10.1194/jlr.D081414