Suboptimal extracellular pH values alter DNA damage response to induced double‐strand breaks

Conditions leading to unrepaired DNA double‐stranded breaks are potent inducers of genetic instability. Systemic conditions may lead to fluctuation of hydrogen ions in the cellular microenvironment, and we show that small variations in extracellular pH, termed suboptimal pHe, can decrease the effici...

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Detalles Bibliográficos
Autores principales: Massonneau, Julien, Ouellet, Camille, Lucien, Fabrice, Dubois, Claire M., Tyler, Jessica, Boissonneault, Guylain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832969/
https://www.ncbi.nlm.nih.gov/pubmed/29511618
http://dx.doi.org/10.1002/2211-5463.12384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832969/
https://www.ncbi.nlm.nih.gov/pubmed/29511618
http://dx.doi.org/10.1002/2211-5463.12384

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