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Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF

DNA repair consists of several cellular pathways which recognize and repair damaged DNA. The classical nonhomologous DNA end‐joining (NHEJ) pathway repairs double‐strand breaks in DNA. It is required for maturation of both B and T lymphocytes by supporting V(D)J recombination as well as B‐cell diffe...

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Detalles Bibliográficos
Autores principales: Gago‐Fuentes, Raquel, Xing, Mengtan, Sæterstad, Siri, Sarno, Antonio, Dewan, Alisa, Beck, Carole, Bradamante, Stefano, Bjørås, Magnar, Oksenych, Valentyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832975/
https://www.ncbi.nlm.nih.gov/pubmed/29511619
http://dx.doi.org/10.1002/2211-5463.12381