Cargando…

Normal development of mice lacking PAXX, the paralogue of XRCC4 and XLF

DNA repair consists of several cellular pathways which recognize and repair damaged DNA. The classical nonhomologous DNA end‐joining (NHEJ) pathway repairs double‐strand breaks in DNA. It is required for maturation of both B and T lymphocytes by supporting V(D)J recombination as well as B‐cell diffe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gago‐Fuentes, Raquel, Xing, Mengtan, Sæterstad, Siri, Sarno, Antonio, Dewan, Alisa, Beck, Carole, Bradamante, Stefano, Bjørås, Magnar, Oksenych, Valentyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832975/ https://www.ncbi.nlm.nih.gov/pubmed/29511619 http://dx.doi.org/10.1002/2211-5463.12381

Ejemplares similares

Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA‐PKcs in human cells
por: Xing, Mengtan, et al.
Publicado: (2019)

Robust DNA repair in PAXX‐deficient mammalian cells
por: Dewan, Alisa, et al.
Publicado: (2018)

Non-Homologous End Joining Factors XLF, PAXX and DNA-PKcs Maintain the Neural Stem and Progenitor Cell Population
por: Gago-Fuentes, Raquel, et al.
Publicado: (2020)

Mediator of DNA Damage Checkpoint Protein 1 Facilitates V(D)J Recombination in Cells Lacking DNA Repair Factor XLF
por: Beck, Carole, et al.
Publicado: (2019)

Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination
por: Lescale, Chloé, et al.
Publicado: (2016)

Role of Paralogue of XRCC4 and XLF in DNA Damage Repair and Cancer Development
por: Tang, Jialin, et al.
Publicado: (2022)

Synthetic lethality between PAXX and XLF in mammalian development
por: Balmus, Gabriel, et al.
Publicado: (2016)

Corrigendum to: Genetic interaction between DNA repair factors PAXX, XLF, XRCC4 and DNA‐PKcs in human cells
Publicado: (2020)

PAXX binding to the NHEJ machinery explains functional redundancy with XLF
por: Seif-El-Dahan, Murielle, et al.
Publicado: (2023)

An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development
por: Roch, Benoit, et al.
Publicado: (2021)

Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren
por: Castañeda-Zegarra, Sergio, et al.
Publicado: (2019)

Erratum for the Research Article: “PAXX binding to the NHEJ machinery explains functional redundancy with XLF”
Publicado: (2023)

Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
por: Castañeda-Zegarra, Sergio, et al.
Publicado: (2020)

PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice
por: Liu, Xiangyu, et al.
Publicado: (2017)

A human XRCC4–XLF complex bridges DNA
por: Andres, Sara N., et al.
Publicado: (2012)

XRCC4's interaction with XLF is required for coding (but not signal) end joining
por: Roy, Sunetra, et al.
Publicado: (2012)

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway
por: Xing, Mengtan, et al.
Publicado: (2015)

XLF-Cernunnos promotes DNA ligase IV–XRCC4 re-adenylation following ligation
por: Riballo, Enriqueta, et al.
Publicado: (2009)

Cdk1 Restrains NHEJ through Phosphorylation of XRCC4-like Factor Xlf1
por: Hentges, Pierre, et al.
Publicado: (2014)

ATM Damage Response and XLF Repair Factor are Functionally Redundant In Joining DNA Breaks
por: Zha, Shan, et al.
Publicado: (2010)

Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ
por: Li, Yi, et al.
Publicado: (2008)

XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair
por: Hammel, Michal, et al.
Publicado: (2011)

Loss of DNA ligase IV prevents recognition of DNA by double-strand break repair proteins XRCC4 and XLF
por: Jayaram, Sumithra, et al.
Publicado: (2008)

Active Components of Commonly Prescribed Medicines Affect Influenza A Virus–Host Cell Interaction: A Pilot Study
por: Ianevski, Aleksandr, et al.
Publicado: (2021)

DrugVirus.info 2.0: an integrative data portal for broad-spectrum antivirals (BSA) and BSA-containing drug combinations (BCCs)
por: Ianevski, Aleksandr, et al.
Publicado: (2022)

PAXX, Not NHEJ1 Is an Independent Prognosticator in Colon Cancer
por: Arora, Mohit, et al.
Publicado: (2020)

Seven classes of antiviral agents
por: Ianevski, Aleksandr, et al.
Publicado: (2022)

Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro
por: Vu, Duc-Duy, et al.
Publicado: (2023)

Novel Synergistic Anti-Enteroviral Drug Combinations
por: Ianevski, Aleksandr, et al.
Publicado: (2022)

Corrigendum to: Robust DNA repair in PAXX‐deficient mammalian cells
Publicado: (2020)

Nafamostat–Interferon-α Combination Suppresses SARS-CoV-2 Infection In Vitro and In Vivo by Cooperatively Targeting Host TMPRSS2
por: Ianevski, Aleksandr, et al.
Publicado: (2021)

Single-stranded DNA ligation and XLF-stimulated incompatible DNA end ligation by the XRCC4-DNA ligase IV complex: influence of terminal DNA sequence
por: Gu, Jiafeng, et al.
Publicado: (2007)

Unique tasks for ribosomal paralogues
por: Leslie, Mitch
Publicado: (2007)

DNA Repair and Immune Response: Editorial
por: Oksenych, Valentyn
Publicado: (2022)

Editorial: Plasticity of immune cells in tumor microenvironment
por: Oksenych, Valentyn
Publicado: (2023)

Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining
por: Normanno, Davide, et al.
Publicado: (2017)

The Non-Homologous End Joining Protein PAXX Acts to Restrict HSV-1 Infection
por: Trigg, Ben J., et al.
Publicado: (2017)

PAXX and its paralogs synergistically direct DNA polymerase λ activity in DNA repair
por: Craxton, Andrew, et al.
Publicado: (2018)

Cernunnos/XLF Deficiency: A Syndromic Primary Immunodeficiency
por: Çipe, Funda Erol, et al.
Publicado: (2014)

Dynamic changes in subcellular localization of cattle XLF during cell cycle, and focus formation of cattle XLF at DNA damage sites immediately after irradiation
por: KOIKE, Manabu, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_evtgl2vte146f8j56ed16fi6j2