Biophysical characterisation of the recombinant human frataxin precursor

Friedreich's ataxia is a disease caused by a decrease in the levels of expression or loss of functionality of the mitochondrial protein frataxin (FXN). The development of an active and stable recombinant variant of FXN is important for protein replacement therapy. Although valuable data about t...

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Detalles Bibliográficos
Autores principales: Castro, Ignacio Hugo, Ferrari, Alejandro, Herrera, María Georgina, Noguera, Martín Ezequiel, Maso, Lorenzo, Benini, Monica, Rufini, Alessandra, Testi, Roberto, Costantini, Paola, Santos, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832983/
https://www.ncbi.nlm.nih.gov/pubmed/29511616
http://dx.doi.org/10.1002/2211-5463.12376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832983/
https://www.ncbi.nlm.nih.gov/pubmed/29511616
http://dx.doi.org/10.1002/2211-5463.12376

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