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miR‐322‐5p targets IGF‐1 and is suppressed in the heart of rats with pulmonary hypertension

Pulmonary arterial hypertension (PAH) is characterised by remodelling of the pulmonary vasculature leading to right ventricular hypertrophy. Here, we show that miR‐322‐5p (the rodent orthologue of miR‐424‐5p) expression is decreased in the right ventricle of monocrotaline‐treated rats, a model of PA...

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Detalles Bibliográficos
Autores principales: Connolly, Martin, Garfield, Benjamin E., Crosby, Alexi, Morrell, Nick W., Wort, Stephen J., Kemp, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832985/
https://www.ncbi.nlm.nih.gov/pubmed/29511611
http://dx.doi.org/10.1002/2211-5463.12369